Journal article
DNAzyme Feedback Amplification: Relaying Molecular Recognition to Exponential DNA Amplification
Abstract
Technologies capable of linking DNA amplification to molecular recognition are very desirable for ultrasensitive biosensing applications. We have developed a simple but powerful isothermal DNA amplification method, termed DNAzyme feedback amplification (DFA), that is capable of relaying molecular recognition to exponential DNA amplification. The method incorporates both an RNA-cleaving DNAzyme (RCD) and rolling circle amplification (RCA) …
Authors
Liu M; Yin Q; McConnell EM; Chang Y; Brennan JD; Li Y
Journal
Chemistry - A European Journal, Vol. 24, No. 18, pp. 4473–4479
Publisher
Wiley
Publication Date
March 26, 2018
DOI
10.1002/chem.201705338
ISSN
0947-6539