Journal article
A Highly Dynamic Loop of the Pseudomonas aeruginosa PA14 Type IV Pilin Is Essential for Pilus Assembly
Abstract
Type IVa pili (T4aP) are long, thin surface filaments involved in attachment, motility, biofilm formation, and DNA uptake. They are important virulence factors for many bacteria, including Pseudomonas aeruginosa, an opportunistic pathogen and common cause of hospital-acquired infections. Each helical filament contains thousands of monomers of the major pilin subunit, PilA. Each P. aeruginosa strain expresses one of five phylogenetically …
Authors
Nguyen Y; Boulton S; McNicholl ET; Akimoto M; Harvey H; Aidoo F; Melacini G; Burrows LL
Journal
ACS Infectious Diseases, Vol. 4, No. 6, pp. 936–943
Publisher
American Chemical Society (ACS)
Publication Date
June 8, 2018
DOI
10.1021/acsinfecdis.7b00229
ISSN
2373-8227