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Epithelial-Derived Cytokines in Asthma
Journal article

Epithelial-Derived Cytokines in Asthma

Abstract

The interaction between the airway epithelium and the inhaled environment is crucial to understanding the pathobiology of asthma. Several studies have identified an important role of airway epithelial-derived cytokines, IL-25, IL-33, and thymic stromal lymphopoietin (TSLP) in asthma pathogenesis. These cytokines have been described as epithelial-derived alarmins that activate and potentiate the innate and humoral arms of the immune system in …

Authors

Mitchell PD; O’Byrne PM

Journal

Chest, Vol. 151, No. 6, pp. 1338–1344

Publisher

Elsevier

Publication Date

6 2017

DOI

10.1016/j.chest.2016.10.042

ISSN

0012-3692