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A Test in Context: D-Dimer
Journal article

A Test in Context: D-Dimer

Abstract

D-dimer is a soluble fibrin degradation product that results from ordered breakdown of thrombi by the fibrinolytic system. Numerous studies have shown that D-dimer serves as a valuable marker of activation of coagulation and fibrinolysis. Consequently, D-dimer has been extensively investigated for the diagnosis of venous thromboembolism (VTE) and is used routinely for this indication. In addition, D-dimer has been evaluated for determining the …

Authors

Weitz JI; Fredenburgh JC; Eikelboom JW

Journal

Journal of the American College of Cardiology, Vol. 70, No. 19, pp. 2411–2420

Publisher

Elsevier

Publication Date

11 2017

DOI

10.1016/j.jacc.2017.09.024

ISSN

0735-1097