Journal article
Th17/Treg ratio derived using DNA methylation analysis is associated with the late phase asthmatic response
Abstract
BackgroundThe imbalance between Th17 and Treg cells has been studied in various diseases including allergic asthma but their roles have not been fully understood in the development of the late phase asthmatic response.ObjectivesTo determine changes in Th17 and Treg cell numbers between isolated early responders (ERs) and dual responders (DRs) undergoing allergen inhalation challenge. To identify gene expression profiles associated with Th17 and …
Authors
Singh A; Yamamoto M; Ruan J; Choi JY; Gauvreau GM; Olek S; Hoffmueller U; Carlsten C; FitzGerald JM; Boulet L-P
Journal
Allergy, Asthma & Clinical Immunology, Vol. 10, No. 1,
Publisher
Springer Nature
Publication Date
December 2014
DOI
10.1186/1710-1492-10-32
ISSN
1710-1484