Journal article
Exercise-induced Bronchoconstriction Does Not Cause Eosinophilic Airway Inflammation or Airway Hyperresponsiveness in Subjects with Asthma
Abstract
The cysteinyl leukotrienes (LT) C(4), D(4), and E(4) may partially mediate eosinophilic airway inflammation in patients with asthma. High- intensity exercise by patients with asthma can result in exercise- induced bronchoconstriction, partly due to leukotriene production, but it is still debated whether this causes airway inflammation. Ten subjects completed a randomized, controlled study to examine the effects of exercise-induced …
Authors
GAUVREAU GM; RONNEN GM; WATSON RM; O'BYRNE PM
Journal
American Journal of Respiratory and Critical Care Medicine, Vol. 162, No. 4, pp. 1302–1307
Publisher
American Thoracic Society
Publication Date
October 1, 2000
DOI
10.1164/ajrccm.162.4.2001054
ISSN
1073-449X