Journal article
Label-Free Fiber Optic Biosensors with Enhanced Sensitivity
Abstract
A sensitivity-enhanced long-period grating in-fiber Michelson interferometer with diameter-reduced cladding was proposed for the first time, and was also demonstrated as a label-free biosensor based on refractive index measurement. The cladding structure dependence of the sensitivity for antibody–antigen immuno-sensing was studied experimentally. The proposed biosensor has shown an 8.5-fold sensitivity enhancement as compared to sensors without …
Authors
Yang J; Sandhu P; Liang W; Xu C-Q; Li Y
Journal
IEEE Journal of Selected Topics in Quantum Electronics, Vol. 13, No. 6, pp. 1691–1696
Publisher
Institute of Electrical and Electronics Engineers (IEEE)
Publication Date
January 1, 2007
DOI
10.1109/jstqe.2007.910999
ISSN
0792-1233