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Biocompatibilities of sapphire and borosilicate...
Journal article

Biocompatibilities of sapphire and borosilicate glass as cortical neuroprostheses

Abstract

The in vivo biocompatibility of pure sapphire and borosilicate glass (BSG) implanted onto the cerebral cortex was studied via magnetic resonance imaging (MRI) and histopathology. Each implant was embedded onto the cortical surface of an adult rat brain for a total of 28 days. Rats underwent surgery with and without implants, and rats with purposely damaged cortical implant sites were also studied. Each animal was imaged via MRI before surgery …

Authors

Parthasarathy KS; Cheng Y-CN; McAllister JP; Shen Y; Li J; Deren K; Haacke EM; Auner GW

Journal

Magnetic Resonance Imaging, Vol. 25, No. 9, pp. 1333–1340

Publisher

Elsevier

Publication Date

11 2007

DOI

10.1016/j.mri.2007.03.020

ISSN

0730-725X