Journal article
The 5-HTTLPR and BDNF polymorphisms moderate the association between uncinate fasciculus connectivity and antidepressants treatment response in major depression
Abstract
Abstract Symptom improvement in depression due to antidepressant treatment is highly variable and clinically unpredictable. Linking neuronal connectivity and genetic risk factors in predicting antidepressant response has clinical implications. Our investigation assessed whether indices of white matter integrity, serotonin transporter-linked polymorphism (5-HTTLPR) and brain-derived neurotrophic factor (BDNF) val66met polymorphism predicted …
Authors
Tatham EL; Hall GBC; Clark D; Foster J; Ramasubbu R
Journal
European Archives of Psychiatry and Clinical Neuroscience, Vol. 267, No. 2, pp. 135–147
Publisher
Springer Nature
Publication Date
March 2017
DOI
10.1007/s00406-016-0702-9
ISSN
0940-1334