Cyclical etidronate therapy in the prevention and treatment of corticosteroid-induced osteoporosis

Corticosteroids are a major cause of osteoporosis, resulting in significant morbidity. This review is an attempt to summarize a very complex field. The pathophysiology of corticosteroid-induced osteoporosis is still not well worked out and the outline provided is a summary of some of the theories expressed in the literature. In reviewing the clinical aspects, most of the trials reviewed involved mixed populations of patients with complicated …