Integrating graphene oxide, functional DNA and nucleic-acid-manipulating strategies for amplified biosensing

Integrating functional DNA probes with graphene oxide (GO) has proved to be a productive approach to the design of optical biosensors that detect nucleic acids, proteins or small-molecule targets. This distinctive methodology neatly combines four intriguing properties associated with DNA and GO:•the functional versatility of DNA sequences as molecular receptors;•the ability of DNA to switch structural forms in a target-responsive manner;•the …