Macroporous Monolithic Methylsilsesquioxanes Prepared by a Two-Step Acid/Acid Processing Method

The development of monolithic methylsilsesquioxane (MSQ) materials with bicontinuous meso-/macroporous morphologies has proven to be advantageous for the fabrication of chromatographic stationary phases. However, it is currently very difficult to obtain suitable columns over a range of capillary sizes, owing to alterations in morphology in narrow diameter capillaries and material shrinkage in large-bore capillaries. Herein, we describe a new …