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Defective repair of UV-damaged DNA in human tumor...
Journal article

Defective repair of UV-damaged DNA in human tumor and SV40-transformed human cells but not in adenovirus-transformed human cells

Abstract

The DNA repair capacities of five human tumor cell lines, one SV40-transformed human cell line and one adenovirus-transformed human cell line were compared with that of normal human fibroblasts using a sensitive host cell reactivation (HCR) technique. Unirradiated and UV-irradiated suspensions of adenovirus type 2 (Ad 2) were assayed for their ability to form viral structural antigens (Vag) in the various cell types using immunofluorescent …

Authors

Rainbow AJ

Journal

Carcinogenesis, Vol. 10, No. 6, pp. 1073–1077

Publisher

Oxford University Press (OUP)

Publication Date

1989

DOI

10.1093/carcin/10.6.1073

ISSN

0143-3334