Experts has a new look! Let us know what you think of the updates.

Provide feedback
Home
Scholarly Works
Capacity of UV‐lrradiated Human Fibroblasts to...
Journal article

Capacity of UV‐lrradiated Human Fibroblasts to Support Adenovirus DNA Synthesis Correlates with Transcription‐Coupled Repair and is Reduced in SV40‐Transformed Cells and Cells Expressing Mutant p53

Abstract

We have examined the capacity of UV-irradiated human diploid fibroblasts to support adenovirus (Ad) DNA synthesis in order to assess repair of UV-damaged DNA. The capacity of UV-irradiated xeroderma pigmentosum group C (XP-C) fibroblasts to support Ad DNA synthesis was similar to that of UV-irradiated normal diploid fibroblasts, following UV exposures of greater than 9 J/m2. In contrast, XP-A, Cockayne syndrome groups A and B (CS-A and CS-B) …

Authors

McKay BC; Winrow C; Rainbow AJ

Journal

Photochemistry and Photobiology, Vol. 66, No. 5, pp. 659–664

Publisher

Wiley

Publication Date

November 1997

DOI

10.1111/j.1751-1097.1997.tb03203.x

ISSN

0031-8655