Journal article
Salt‐induced changes in plasmid DNA transmission through ultrafiltration membranes
Abstract
Recent studies have demonstrated the feasibility of using ultrafiltration for the purification of plasmid DNA, but there is still little understanding of the factors governing DNA transmission. Experimental data were obtained for the transmission of a 3.0 kbp supercoiled plasmid DNA through composite regenerated cellulose ultrafiltration membranes as a function of solution ionic environment in a stirred ultrafiltration cell. The dependence on …
Authors
Latulippe DR; Zydney AL
Journal
Biotechnology and Bioengineering, Vol. 99, No. 2, pp. 390–398
Publisher
Wiley
Publication Date
2 2008
DOI
10.1002/bit.21575
ISSN
0006-3592