Interaction of fibrinogen with solid surfaces of varying charge and hydrophobic—hydrophilic balance I. Adsorption isotherms

Adsorption of fibrinogen to a series of polyelectrolyte complex surfaces of varying charge density (bulk ion-exchange capacity ranging from +1.21 to −1.33 meq g−1) and hydrophilicity (water content from 4.5 to 60 wt%) was studied using an iodine-labeling technique under static conditions. In the high concentration region of the isotherms (c > 0.5 mg ml−1) pseudoplateaux were observed with adsorption values in the range expected for a …