Journal article
Non-coding RNAs as antibiotic targets
Abstract
Antibiotics inhibit a wide range of essential processes in the bacterial cell, including replication, transcription, translation and cell wall synthesis. In many instances, these antibiotics exert their effects through association with non-coding RNAs. This review highlights many classical antibiotic targets (e.g. rRNAs and the ribosome), explores a number of emerging targets (e.g. tRNAs, RNase P, riboswitches and small RNAs), and discusses the …
Authors
Colameco S; Elliot MA
Journal
Biochemical Pharmacology, Vol. 133, , pp. 29–42
Publisher
Elsevier
Publication Date
June 2017
DOI
10.1016/j.bcp.2016.12.015
ISSN
0006-2952