Journal article
In vitro drug release of natamycin from β-cyclodextrin and 2-hydroxypropyl-β-cyclodextrin-functionalized contact lens materials
Abstract
PURPOSE: The antifungal agent natamycin can effectively form inclusion complexes with beta-cyclodextrin (β-CD) and 2-hydroxypropyl-β-cyclodextrin (HP-βCD) to improve the water solubility of natamycin by 16-fold and 152-fold, respectively (Koontz, J. Agric. Food. Chem. 2003). The purpose of this study was to develop contact lens materials functionalized with methacrylated β-CD (MβCD) and methacrylated HP-βCD (MHP-βCD), and to evaluate their …
Authors
Phan C-M; Subbaraman LN; Jones L
Journal
Journal of Biomaterials Science Polymer Edition, Vol. 25, No. 17, pp. 1907–1919
Publisher
Taylor & Francis
Publication Date
November 22, 2014
DOI
10.1080/09205063.2014.958016
ISSN
0920-5063