Journal article
The Activation of Imines to Nucleophilic Attack by Grignard Reagents
Abstract
The reaction of trimethylsilyl trifluoromethanesulfonate (trimethylsilyl triflate, TMSOTf) with imines leads to the formation of N-trimethylsilyliminium salts which react efficiently with soft nucleophiles to form secondary amines.
Authors
Brook MA; Jahangir
Journal
Synthetic Communications, Vol. 18, No. 9, pp. 893–898
Publisher
Taylor & Francis
Publication Date
6 1988
DOI
10.1080/00397918808060872
ISSN
0039-7911