Generic, S N 2 reactive silicone surfaces protected by poly(ethylene glycol) linkers: facile routes to new materials

The efficacy of biomaterials is frequently dependent upon the interface between a synthetic material and the surrounding biology. While silicones offer many benefits in biomaterials applications, they can suffer from insufficient hydrophilicity. We present a controlled and generic route to the surface modification of silicones that permits the introduction of a passivating poly(ethylene glycol) (PEG) layer capped with biologically relevant …