Development of Macroporous Titania Monoliths Using a Biocompatible Method. Part 1: Material Fabrication and Characterization

Monolithic titania could offer significant potential as a support for bioaffinity chromatography because of its stability, unlike silica, to a wide range of pH conditions and its ability to selectively bind phosphorylated proteins and peptides. However, traditional routes to monolithic titania utilize harsh conditions incompatible with most biomolecules. To address this, titania monoliths were prepared in a biocompatible sol−gel process from …