selected scholarly activity
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chapters
- The Scavenger Receptor Class B Type I: An HDL Receptor Involved in Lipid Transport and HDL Dependent Signaling. 153-178. 2010
- Chapter 8 The Scavenger Receptor Class B Type I An HDL Receptor Involved in Lipid Transport and HDL Dependent Signaling. 153-178. 2010
- The Scavenger Receptor Class B Type I. 153-178. 2010
- Role of the Scavenger Receptor Class B Type I in Lipoprotein Metabolism and Atherosclerosis: Insight from Genetically Altered Mice. 53-69. 2006
- Identification of high affinity membrane-bound fatty acid-binding proteins using a photoreactive fatty acid. 39-44. 1993
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conferences
- Hepatic Cholesterol Dysregulation in SR-B1/ApoE dKO Mice. Atherosclerosis Plus. 38-39. 2018
- High Density Lipoprotein Mediated Protection of Macrophages against Apoptosis Requires Scavenger Receptor Class B Type 1 Activity and Sphingosine-1-Phosphate. Atherosclerosis Plus. 34-34. 2018
- Loss-of-function PCSK9 Mutants Evade the Unfolded Protein Response Sensor, GRP78, and Fail to Induce Endoplasmic Reticulum Stress when Retained. Atherosclerosis Plus. 139-139. 2018
- Scavenger Class B Type 1 Knockout Mice Develop Extensive Diet-Induced Aortic Sinus and Coronary Artery Atherosclerosis in an Age-Dependent Manner. Atherosclerosis Plus. 95-96. 2018
- PCSK9 REDUCES HEPATIC LIPID CONTENT AND CONFERS PROTECTION AGAINST ER STRESS AND ROS IN HEPG2 CELLS. The FASEB Journal. 2018
- Cardioprotective Effects of Interleukin-15 in Immortalized Human Ventricular Cardiomyocytes. Circulation Research. 2015
- Impact of the endothelial protein C receptor in coagulation, inflammation and hematopoiesis. Journal of Thrombosis and Haemostasis. 75-75. 2015
- SR-BI in Bone Marrow-Derived Cells Protects Mice From Diet-Induced Coronary Artery Atherosclerosis and Myocardial Infarction. Arteriosclerosis, Thrombosis and Vascular Biology. 2014
- The Effects of Diet on Occlusive Coronary Artery Atherosclerosis, Thrombosis and Myocardial Infarction in SR-BI/LDL Receptor Double KO Mice. Arteriosclerosis, Thrombosis and Vascular Biology. 2014
- High-density lipoprotein signaling in macrophages and its role in atherosclerosis protection. International Journal of Molecular Medicine. S79-S79. 2014
- Effect of Diabetes on Atherosclerosis and Myocardial Infarction in SR-BI-/-APOE Hypomorphic Mice. Canadian Journal of Cardiology. S175-S176. 2013
- Interleukin 15 Plays an Important Role in the Development of Atherosclerosis in Mice. Canadian Journal of Cardiology. S172-S173. 2013
- Kidney and Blood Pressure Abnormalities and Cardiac Hypertrophy, Accompany Moderate Coronary Artery Atherosclerosis in Western Diet Fed SR-BI/LDLR Double Knockout Mice. Canadian Journal of Cardiology. S176-S177. 2013
- SR-BI in Bone Marrow Derived Cells Protects Mice From Diet Induced Coronary Artery Atherosclerosis and Myocardial Infarction. Canadian Journal of Cardiology. S268-S268. 2013
- Sr-bi Deficiency is Associated with Dendritic Cell Retention in Arterial Atherosclerotic Plagues and Impaired Atherosclerotic Regression in Apoe-r61 Hypomorphic Mice. Circulation. 2012
- 418 Expression of SR-BI in Bone Marrow Derived Cells Protects Against Diet-Induced Coronary Artery Atherosclerosis in SR-BI−/−apoE-R61-Hypomorphic Mice. Canadian Journal of Cardiology. S256-S256. 2012
- 524 Scavenger Receptor Class B Type I Protects Against Doxorubicin Induced Cardiomyocyte Apoptosis. Canadian Journal of Cardiology. S294-S294. 2012
- 486 Interleukin 15 promotes atherosclerosis in apolipoprotein E knockout mice. Canadian Journal of Cardiology. S238-S238. 2011
- 368 INTERLEUKIN 15 PLAYS AN IMPORTANT ROLE IN ATHEROGENESIS IN APOLIPOPROTEIN E KNOCKOUT MICE. Atherosclerosis Plus. 79-79. 2011
- SR-BI/LDL Receptor Double KO Mice Develop Occlusive Coronary Artery Atherosclerosis When Fed High-Fat, High-Cholesterol Diets. Arteriosclerosis, Thrombosis and Vascular Biology. E294-E295. 2010
- PS2-04 Oncostatin M induces interleukin-1R1, interleukin-17 receptor a and synergistic responses to IL-1 and IL-17A ligands in mouse aortic adventitial fibroblasts. Cytokine. 50-51. 2010
- MS541 INTERLEUKIN 15 (IL15) DEFICIENCY DECREASES ATHEROSCLEROSIS IN APOLIPOPROTEIN E KNOCKOUT MICE (APOE KO). Atherosclerosis Plus. 218-219. 2010
- 67. Immune cell phenotypes and cytokine response in a mouse model of sialidase deficiency. Molecular Genetics and Metabolism. S22-S22. 2010
- 68. Impact of tumor necrosis factor-alpha deletion on astrolgliosis and microgliosis in the CNS of Sandhoff mice. Molecular Genetics and Metabolism. S22-S22. 2010
- 132 Oncostatin M induces interleukin-17 receptor a and synergistic responses to interleukin-17 in mouse aortic adventitial fibroblasts. Cytokine. 267-267. 2008
- Enhanced cellular uptake of remnant HDL particles: A mechanism for HDL lowering in insulin resistance and hypertriglyceridemia. Diabetes. A252-A252. 2008
- High-density lipoproteins stimulate the migration of macrophages in a scavenger receptor class B type I-dependent manner. Arteriosclerosis, Thrombosis and Vascular Biology. E92-E92. 2008
- Protein kinase C inhibitors reduce SR-BI dependent HDL lipid uptake in HepG2 cells overexpressing human SR-BI. Canadian Journal of Cardiology. 51C-51C. 2007
- PO22-699 PREVENTION OF ATHEROSCLEROSIS IN APOE KNOCKOUT MICE USING SIALIDASE INHIBITORS: A NEW CLASS OF ANTI-ATHEROGENIC DRUGS. Atherosclerosis Plus. 187-187. 2007
- Hepatic steatosis and inflammation: Role of western diet and lipoproteins. The FASEB Journal. A846-A846. 2007
- Studies on the Properties and Co-immobilization of Manganese Peroxidase. Shengwu Gongcheng Xuebao/Chinese Journal of Biotechnology. 90-96. 2007
- Th-W60:6 Tissue-specific sialidase deficiency protects against atherosclerosis in experimental animals. Atherosclerosis Plus. 488-488. 2006
- Scavenger receptor class B type I in high-density lipoprotein metabolism, atherosclerosis and heart disease: lessons from gene-targeted mice. Biochemical Society Transactions. 116-120. 2004
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journal articles
- Small Molecules Targeting GRP78 Mitigate Anti- GRP78 Autoantibody-Mediated Tissue Factor Procoagulant Activity in Cultured Endothelial Cells. Journal of Thrombosis and Haemostasis. 22:3290-3304. 2024
- Ligand-dependent interactions between SR-B1 and S1PR1 in macrophages and atherosclerotic plaques. Journal of Lipid Research. 65:100541-100541. 2024
- Bystander activated CD8+ T cells mediate neuropathology during viral infection via antigen-independent cytotoxicity. Nature Communications. 15:896. 2024
- PAR4 Inhibition Reduces Coronary Artery Atherosclerosis and Myocardial Fibrosis in SR-B1/LDLR Double Knockout Mice. Arteriosclerosis, Thrombosis and Vascular Biology. 43:2165-2178. 2023
- Apolipoprotein A1 Protects Against Necrotic Core Development in Atherosclerotic Plaques: PDZK1-Dependent High-Density Lipoprotein Suppression of Necroptosis in Macrophages. Arteriosclerosis, Thrombosis and Vascular Biology. 43:45-63. 2023
- Acknowledgement to Reviewers of Immunometabolism in 2021. Immunometabolism (United States). 4. 2022
- Extensive diet-induced atherosclerosis in scavenger receptor class B type 1-deficient mice is associated with substantial leukocytosis and elevated vascular cell adhesion molecule-1 expression in coronary artery endothelium. Frontiers in Physiology. 13:1023397. 2022
- Pcpe2: A New Partner for the Scavenger Receptor Class B Type I in High-Density Lipoprotein Selective Lipid Uptake. Arteriosclerosis, Thrombosis and Vascular Biology. 41:2726-2729. 2021
- Salsalate reduces atherosclerosis through AMPKβ1 in mice. Molecular Metabolism. 53:101321-101321. 2021
- Good Cholesterol Gone Bad? HDL and COVID-19. International Journal of Molecular Sciences. 22:10182-10182. 2021
- Biomarkers of coagulation, endothelial function, and fibrinolysis in critically ill patients with COVID‐19: A single‐center prospective longitudinal study. Journal of Thrombosis and Haemostasis. 19:1546-1557. 2021
- The local effects of proprotein convertase subtilisin/kexin type 9 (PCSK9) on the inflammatory atheroma: beyond LDL cholesterol lowering. Vessel Plus. 5:5-5. 2021
- High Density Lipoprotein and Its Precursor Protein Apolipoprotein A1 as Potential Therapeutics to Prevent Anthracycline Associated Cardiotoxicity. Frontiers in Cardiovascular Medicine. 7:65. 2020
- Pcsk9 knockout exacerbates diet-induced non-alcoholic steatohepatitis, fibrosis and liver injury in mice. JHEP Reports. 1:418-429. 2019
- Proceedings of the Ninth HDL (High-Density Lipoprotein) Workshop. Arteriosclerosis, Thrombosis and Vascular Biology. 39:2457-2467. 2019
- Un-JAMming atherosclerotic arteries: JAM-L as a target to attenuate plaque development. Clinical Science. 133:1581-1585. 2019
- Treatment with apolipoprotein A1 protects mice against doxorubicin-induced cardiotoxicity in a scavenger receptor class B, type I-dependent manner. American Journal of Physiology. Heart and Circulatory Physiology. 316:H1447-H1457. 2019
- PDZK1 in leukocytes protects against cellular apoptosis and necrotic core development in atherosclerotic plaques in high fat diet fed ldl receptor deficient mice. Atherosclerosis. 276:171-181. 2018
- Sialidase down-regulation reduces non-HDL cholesterol, inhibits leukocyte transmigration, and attenuates atherosclerosis in ApoE knockout mice. Journal of Biological Chemistry. 293:14689-14706. 2018
- Data on leukocyte PDZK1 deficiency affecting macrophage apoptosis but not monocyte recruitment, cell proliferation, macrophage abundance or ER stress in atherosclerotic plaques of LDLR deficient mice. Data in Brief. 19:1148-1161. 2018
- Low-density lipoprotein (LDL)-dependent uptake of Gram-positive lipoteichoic acid and Gram-negative lipopolysaccharide occurs through LDL receptor. Scientific Reports. 8:10496. 2018
- Effects of Hematopoietic Deficiency of Pro-apoptotic Protein Bim on the Development of Atherosclerosis. Atherosclerosis Plus. 32:100-100. 2018
- Loss-of-function PCSK9 mutants evade the unfolded protein response sensor GRP78 and fail to induce endoplasmic reticulum stress when retained. Journal of Biological Chemistry. 293:7329-7343. 2018
- High-density lipoprotein protects cardiomyocytes against necrosis induced by oxygen and glucose deprivation through SR-B1, PI3K, and AKT1 and 2. Biochemical Journal. 475:1253-1265. 2018
- Loss‐of‐function PCSK9 mutants evade the unfolded protein response sensor, GRP78, and fail to induce endoplasmic reticulum stress when retained. The FASEB Journal. 32:793.7-793.7. 2018
- PCSK9 REDUCES HEPATIC LIPID CONTENT AND CONFERS PROTECTION AGAINST ER STRESS AND ROS IN HEPG2 CELLS. The FASEB Journal. 32:539.8-539.8. 2018
- HDL protects against doxorubicin-induced cardiotoxicity in a scavenger receptor class B type 1-, PI3K-, and Akt-dependent manner. American Journal of Physiology. Heart and Circulatory Physiology. 314:H31-H44. 2018
- Hyperglycemia Aggravates Diet-Induced Coronary Artery Disease and Myocardial Infarction in SR-B1-Knockout/ApoE-Hypomorphic Mice. Frontiers in Physiology. 9:1398. 2018
- Rosuvastatin Reduces Aortic Sinus and Coronary Artery Atherosclerosis in SR-B1 (Scavenger Receptor Class B Type 1)/ApoE (Apolipoprotein E) Double Knockout Mice Independently of Plasma Cholesterol Lowering. Arteriosclerosis, Thrombosis and Vascular Biology. 38:26-39. 2018
- Sphingosine-1-Phosphate Receptor 1, Expressed in Myeloid Cells, Slows Diet-Induced Atherosclerosis and Protects against Macrophage Apoptosis in Ldlr KO Mice. International Journal of Molecular Sciences. 18:2721-2721. 2017
- Abstract 407: High Density Lipoprotein Mediated Protection of Macrophages Against Apoptosis Requires Scavenger Receptor Class B Type 1 Activity and Sphingosine-1-Phosphate. Arteriosclerosis, Thrombosis and Vascular Biology. 37. 2017
- Abstract 602: High-Density Lipoprotein Protects Macrophages Against Apoptosis Through BH3-only Bcl-2 Family Member Bim. Arteriosclerosis, Thrombosis and Vascular Biology. 37. 2017
- Suppression of NK and CD8+ T cells reduces astrogliosis but accelerates cerebellar dysfunction and shortens life span in a mouse model of Sandhoff disease. Journal of Neuroimmunology. 306:55-67. 2017
- SR-B1 and PDZK1: partners in HDL regulation. Current Opinion in Lipidology. 28:201-208. 2017
- Macrophage Apoptosis and Necrotic Core Development in Atherosclerosis: A Rapidly Advancing Field with Clinical Relevance to Imaging and Therapy. Canadian Journal of Cardiology. 33:303-312. 2017
- Endoplasmic Reticulum Stress and Ca2+ Depletion Differentially Modulate the Sterol Regulatory Protein PCSK9 to Control Lipid Metabolism. Journal of Biological Chemistry. 292:1510-1523. 2017
- Endoplasmic Reticulum Stress and Ca2+ Depletion Differentially Modulate the Sterol Regulatory Protein PCSK9 to Control Lipid Metabolism. Journal of Biological Chemistry. 292:1510-1523. 2017
- Characterization of Proliferating Lesion‐Resident Cells During All Stages of Atherosclerotic Growth. Journal of the American Heart Association. 5:e003945. 2016
- Rare Genetic Variants and High-Density Lipoprotein. Arteriosclerosis, Thrombosis and Vascular Biology. 36:e53-e55. 2016
- HDL signaling and protection against coronary artery atherosclerosis in mice. Journal of Biomedical Research. 30:94-94. 2016
- Intestinal scavenger receptor class B type I as a novel regulator of chylomicron production in healthy and diet-induced obese states. American Journal of Physiology - Gastrointestinal and Liver Physiology. 309:G350-G359. 2015
- Characterization of mice harboring a variant of EPCR with impaired ability to bind protein C: novel role of EPCR in hematopoiesis. Blood. 126:673-682. 2015
- Abstract 18: Increasing in vivo Apoa1/HDL Levels Negates the Cardiotoxic Effects of Doxorubicin, and Involves Signalling Through SR-BI, PI3K, and AKT1. Circulation Research. 117. 2015
- Abstract 415: Cardioprotective Effects of Interleukin-15 in Immortalized Human Ventricular Cardiomyocytes. Circulation Research. 117. 2015
- Abstract 559: FTY720 Protects Against Diet Induced Coronary Artery Disease and Myocardial Infarction in Diabetic SR-B1-/- ApoE-Hypomorphic Mice. Arteriosclerosis, Thrombosis and Vascular Biology. 35. 2015
- Correction: High Density Lipoprotein Stimulated Migration of Macrophages Depends on the Scavenger Receptor Class B, Type I, PDZK1 and Akt1 and Is Blocked by Sphingosine 1 Phosphate Receptor Antagonists. PLoS ONE. 10:e0117623-e0117623. 2015
- The Effects of Diet on Occlusive Coronary Artery Atherosclerosis and Myocardial Infarction in Scavenger Receptor Class B, Type 1/Low-Density Lipoprotein Receptor Double Knockout Mice. Arteriosclerosis, Thrombosis and Vascular Biology. 34:2394-2403. 2014
- Abstract 284: A Deficiency in the HDL Receptor SR-BI Attenuates Atherosclerotic Plaque Regression in ApoE-Hypomorphic Mice. Arteriosclerosis, Thrombosis and Vascular Biology. 34. 2014
- Abstract 428: Scavenger Receptor Class B Type I Is Required for Protection by High-Density Lipoprotein Against Doxorubicin-Induced Apoptosis in Both Mouse and Human Cardiomyocytes and Cardiotoxicity in Mice. Arteriosclerosis, Thrombosis and Vascular Biology. 34. 2014
- Abstract 455: The Effects of Diet on Occlusive Coronary Artery Atherosclerosis, Thrombosis and Myocardial Infarction in SR-BI/LDL Receptor Double KO Mice. Arteriosclerosis, Thrombosis and Vascular Biology. 34. 2014
- Abstract 50: High-Density Lipoprotein Protects Macrophages Against Apoptosis in a PDZK1-Dependent Manner. Arteriosclerosis, Thrombosis and Vascular Biology. 34. 2014
- Abstract 641: Interleukin-15 Plays a Role in Atherosclerosis Through Effects on Multiple Inflammatory Cells in ApoE-/- Mice. Arteriosclerosis, Thrombosis and Vascular Biology. 34. 2014
- Abstract 647: Hyperglycemia Increases Diet-Induced Coronary Artery Disease and Myocardial Infarction in SRBI Knockout ApoE-Hypomorphic Mice. Arteriosclerosis, Thrombosis and Vascular Biology. 34. 2014
- Abstract 669: SR-BI in Bone Marrow--Derived Cells Protects Mice From Diet-Induced Coronary Artery Atherosclerosis and Myocardial Infarction. Arteriosclerosis, Thrombosis and Vascular Biology. 34. 2014
- High Density Lipoprotein Stimulated Migration of Macrophages Depends on the Scavenger Receptor Class B, Type I, PDZK1 and Akt1 and Is Blocked by Sphingosine 1 Phosphate Receptor Antagonists. PLoS ONE. 9:e106487-e106487. 2014
- Interleukin-15 Modulates Adipose Tissue by Altering Mitochondrial Mass and Activity. PLoS ONE. 9:e114799-e114799. 2014
- Deletion of tumor necrosis factor-α ameliorates neurodegeneration in Sandhoff disease mice. Human Molecular Genetics. 22:3960-3975. 2013
- Hdl Protects Macrophages Against Apoptosis in a PDZK1-Dependent Manner. Canadian Journal of Cardiology. 29:S166-S166. 2013
- SR-BI and Its Adaptor Protein PDZK1 Are Required for HDL-Mediated Protection Against Doxorubicin Induced Cardiomyocyte Apotosis. Canadian Journal of Cardiology. 29:S178-S179. 2013
- Deficiency of TDAG51 Protects Against Atherosclerosis by Modulating Apoptosis, Cholesterol Efflux, and Peroxiredoxin‐1 Expression. Journal of the American Heart Association. 2:e000134. 2013
- Abstract 134: Kidney and Blood Pressure Abnormalities, and Cardiac Enlargement Accompany Moderate Coronary Artery Atherosclerosis in Western Diet Fed SR-BI/LDLR Double Knockout Mice. Arteriosclerosis, Thrombosis and Vascular Biology. 33. 2013
- The effect of pomegranate extract on coronary artery atherosclerosis in SR-BI/APOE double knockout mice. Atherosclerosis. 228:80-89. 2013
- Oncostatin M and TLR-4 Ligand Synergize to Induce MCP-1, IL-6, and VEGF in Human Aortic Adventitial Fibroblasts and Smooth Muscle Cells. Mediators of Inflammation. 2013:1-14. 2013
- SR-BI in Bone Marrow Derived Cells Protects Mice from Diet Induced Coronary Artery Atherosclerosis and Myocardial Infarction. PLoS ONE. 8:e72492-e72492. 2013
- Hypomorphic sialidase expression decreases serum cholesterol by downregulation of VLDL production in mice. Journal of Lipid Research. 53:2573-2585. 2012
- Abstract 19004: Sr-bi Deficiency is Associated with Dendritic Cell Retention in Arterial Atherosclerotic Plagues and Impaired Atherosclerotic Regression in Apoe-r61 Hypomorphic Mice. Circulation. 126. 2012
- Abstract 337: Extensive Coronary Artery Atherosclerosis and Myocardial Infarction in SR-BI/LDLR Double Knockout Mice Fed 4 Different Atherogenic Diets. Arteriosclerosis, Thrombosis and Vascular Biology. 32. 2012
- Abstract 80: Interleukin 15 Plays an Important Role in the Development of Atherosclerosis in Apolipoprotein E Knockout Mice. Arteriosclerosis, Thrombosis and Vascular Biology. 32. 2012
- Modifications in Perfringolysin O Domain 4 Alter the Cholesterol Concentration Threshold Required for Binding. Biochemistry. 51:3373-3382. 2012
- Intestinal SR-BI is upregulated in insulin-resistant states and is associated with overproduction of intestinal apoB48-containing lipoproteins. American Journal of Physiology - Gastrointestinal and Liver Physiology. 301:G326-G337. 2011
- Lipoprotein enrichment in orange insoluble particulate matter reproducibly appearing in cryoprecipitate. Vox Sanguinis. 100:422-425. 2011
- Modulators of Protein Kinase C Affect SR-BI-Dependent HDL Lipid Uptake in Transfected HepG2 Cells. Cholesterol. 2011:1-11. 2011
- A role for the scavenger receptor, class B type I in high density lipoprotein dependent activation of cellular signaling pathways. Biochimica et Biophysica Acta: international journal of biochemistry and biophysics. 1801:1239-1248. 2010
- Interleukin‐15 Contributes to the Regulation of Murine Adipose Tissue and Human Adipocytes. Obesity. 18:1601-1607. 2010
- Abstract: P643 INTERLEUKIN 15 DEFICIENCY DECREASES ATHEROSCLEROSIS IN APOLIPOPROTEIN E KNOCKOUT MICE. Atherosclerosis Plus. 10:e829-e829. 2009
- Hepatic uptake and metabolism of phosphatidylcholine associated with high density lipoproteins. Biochimica et Biophysica Acta: international journal of biochemistry and biophysics. 1790:538-551. 2009
- A point mutation in the neu1 promoter recruits an ectopic repressor, Nkx3.2 and results in a mouse model of sialidase deficiency. Molecular Genetics and Metabolism. 97:43-52. 2009
- Enhanced Cellular Uptake of Remnant High-Density Lipoprotein Particles. Circulation Research. 103:159-166. 2008
- Hyperhomocysteinemia induced by methionine supplementation does not independently cause atherosclerosis in C57BL/6J mice. The FASEB Journal. 22:2569-2578. 2008
- Conversion of Low Density Lipoprotein-associated Phosphatidylcholine to Triacylglycerol by Primary Hepatocytes. Journal of Biological Chemistry. 283:6449-6458. 2008
- Myocardial Infarction Following Atherosclerosis in Murine Models. Current Drug Targets. 9:217-223. 2008
- Liver X Receptor Stimulates Cholesterol Efflux and Inhibits Expression of Proinflammatory Mediators in Human Airway Smooth Muscle Cells. Molecular Endocrinology. 21:1324-1334. 2007
- Liver X receptor stimulates cholesterol efflux and inhibits expression of proinflammatory mediators in human airway smooth muscle cells. Molecular Endocrinology. 21:1324-1334. 2007
- Cholesterol depletion inhibits fatty acid uptake without affecting CD36 or caveolin-1 distribution in adipocytes. Biochemical and Biophysical Research Communications. 355:67-71. 2007
- Regulation of SR-BI-mediated selective lipid uptake in Chinese hamster ovary-derived cells by protein kinase signaling pathways. Journal of Lipid Research. 48:405-416. 2007
- The inhibition of endocytosis affects HDL-lipid uptake mediated by the human scavenger receptor class B type I. Molecular Membrane Biology. 24:442-454. 2007
- Expression of a functional extracellular calcium-sensing receptor in human aortic endothelial cells. Biochemical and Biophysical Research Communications. 342:153-163. 2006
- Hepatic Lipase Deficiency Delays Atherosclerosis, Myocardial Infarction, and Cardiac Dysfunction and Extends Lifespan in SR-BI/Apolipoprotein E Double Knockout Mice. Arteriosclerosis, Thrombosis and Vascular Biology. 26:548-554. 2006
- Glucosamine-Induced Endoplasmic Reticulum Dysfunction Is Associated With Accelerated Atherosclerosis in a Hyperglycemic Mouse Model. Diabetes. 55:93-101. 2006
- Hepatic high-density lipoprotein receptors: Roles in lipoprotein metabolism and potential for therapeutic modulation. Current Atherosclerosis Reports. 7:344-350. 2005
- Biochemical Demonstration of the Involvement of Fatty Acyl-CoA Synthetase in Fatty Acid Translocation across the Plasma Membrane. Journal of Biological Chemistry. 279:24163-24170. 2004
- Influence of the HDL Receptor SR-BI on Lipoprotein Metabolism and Atherosclerosis. Arteriosclerosis, Thrombosis and Vascular Biology. 23:1732-1738. 2003
- Scavenger Receptor Class B Type I–Mediated Protection Against Atherosclerosis in LDL Receptor–Negative Mice Involves Its Expression in Bone Marrow–Derived Cells. Arteriosclerosis, Thrombosis and Vascular Biology. 23:1589-1594. 2003
- Failure of red blood cell maturation in mice with defects in the high-density lipoprotein receptor SR-BI. Blood. 99:1817-1824. 2002
- Failure of red blood cell maturation in mice with defects in the high-density lipoprotein receptor SR-BI. Blood. 99:1817-1824. 2002
- Loss of SR-BI Expression Leads to the Early Onset of Occlusive Atherosclerotic Coronary Artery Disease, Spontaneous Myocardial Infarctions, Severe Cardiac Dysfunction, and Premature Death in Apolipoprotein E–Deficient Mice. Circulation Research. 90:270-276. 2002
- Hepatic cholesterol and bile acid metabolism and intestinal cholesterol absorption in scavenger receptor class B type I (SR-BI)-deficient mice. Gastroenterology. 120:A65-A65. 2001
- Hepatic cholesterol and bile acid metabolism and intestinal cholesterol absorption in scavenger receptor class B type I (SR-BI)-deficient mice. Gastroenterology. 120:A65-A65. 2001
- Hepatic cholesterol and bile acid metabolism and intestinal cholesterol absorption in scavenger receptor class B type I-deficient mice. Journal of Lipid Research. 42:170-180. 2001
- Cellular and physiological roles of SR-BI, a lipoprotein receptor which mediates selective lipid uptake. Biochimica et Biophysica Acta: international journal of biochemistry and biophysics. 1529:276-286. 2000
- The role of the high-density lipoprotein receptor SR-BI in cholesterol metabolism. Current Opinion in Lipidology. 11:123-131. 2000
- Scavenger receptor class B type I (SR-BI) and high-density lipoprotein metabolism: recent lessons from genetically manipulated mice.. International Journal of Tissue Reactions. 22:29-37. 2000
- Influence of the high density lipoprotein receptor SR-BI on reproductive and cardiovascular pathophysiology. Proceedings of the National Academy of Sciences of the United States of America. 96:9322-9327. 1999
- Identification of Caveolin-1 as a Fatty Acid Binding Protein. Biochemical and Biophysical Research Communications. 255:34-39. 1999
- Erratum: The efficient cellular uptake of high density lipoprotein lipids via scavenger receptor class B type I requires not only receptor- mediated surface binding but also receptor-specific lipid transfer mediated by its extracellular domain (Journal of Biological Chemistry (1998) 273 (26538-26348)). Journal of Biological Chemistry. 273:35388. 1998
- The efficient cellular uptake of high density lipoprotein lipids via scavenger receptor class B type I requires not only receptor-mediated surface binding but also receptor-specific lipid transfer mediated by its extracellular domain (vol 273, pg 26343, 1998). Journal of Biological Chemistry. 273:35388-35388. 1998
- The efficient cellular uptake of high density lipoprotein lipids via scavenger receptor class B type I requires not only receptor-mediated surface binding but also receptor-specific lipid transfer mediated by its extracellular domain.. Journal of Biological Chemistry. 273:35388-35388. 1998
- The Efficient Cellular Uptake of High Density Lipoprotein Lipids via Scavenger Receptor Class B Type I Requires Not Only Receptor-mediated Surface Binding but Also Receptor-specific Lipid Transfer Mediated by Its Extracellular Domain. Journal of Biological Chemistry. 273:26338-26348. 1998
- Erratum: Scavenger receptor class B, type I (SR-BI) is the major route for the delivery of high density lipoprotein cholesterol to the steroidogenic pathway in cultured mouse adrenocortical cells (Proceedings of the National Academy of Sciences of the United States of America (December 4, 1997) 94:25 (13600-13605)). Proceedings of the National Academy of Sciences of the United States of America. 95:5841. 1998
- Scavenger receptor class B, type I (SR-BI) is the major route for the delivery of high density lipoprotein cholesterol to the steroidogenic pathway in cultured mouse adrenocortical cells (vol 94, pg 13600, 1997). Proceedings of the National Academy of Sciences of the United States of America. 95:5841-5841. 1998
- Scavenger receptor class B, type I (SR-BI) is the major route for the delivery of high density lipoprotein cholesterol to the steroidogenic pathway in cultured mouse adrenocortical cells. Proceedings of the National Academy of Sciences of the United States of America. 94:13600-13605. 1997
- A targeted mutation in the murine gene encoding the high density lipoprotein (HDL) receptor scavenger receptor class B type I reveals its key role in HDL metabolism. Proceedings of the National Academy of Sciences of the United States of America. 94:12610-12615. 1997
- Scavenger receptor Bl - a cell surface receptor for high density lipoprotein. Current Opinion in Lipidology. 8:181-188. 1997
- Murine SR-BI, a High Density Lipoprotein Receptor That Mediates Selective Lipid Uptake, Is N-Glycosylated and Fatty Acylated and Colocalizes with Plasma Membrane Caveolae. Journal of Biological Chemistry. 272:13242-13249. 1997
- A Single Point Mutation in ϵ-COP Results in Temperature-sensitive, Lethal Defects in Membrane Transport in a Chinese Hamster Ovary Cell Mutant. Journal of Biological Chemistry. 271:11191-11196. 1996
- The effect of intracellular pH on long-chain fatty acid uptake in 3T3-L1 adipocytes: evidence that uptake involves the passive diffusion of protonated long-chain fatty acids across the plasma membrane. Biochemical Journal. 313:487-494. 1996
- A direct role for serum albumin in the cellular uptake of long-chain fatty acids. Biochemical Journal. 308:155-159. 1995
- Membrane permeation and intracellular trafficking of long chain fatty acids: insights fromEscherichia coliand 3T3-L1 adipocytes. Biochemistry and Cell Biology. 73:223-234. 1995
- Identification of high affinity membrane-bound fatty acid-binding proteins using a photoreactive fatty acid. Molecular and Cellular Biochemistry. 123:39-44. 1993
- Fatty acid uptake in Candida tropicalis: induction of a saturable process. Biochemistry and Cell Biology. 70:76-80. 1992
- Photoaffinity labeling and fatty acid permeation in 3T3-L1 adipocytes.. Journal of Biological Chemistry. 266:22621-22625. 1991
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theses