A study was designed to explore the relationship between occupation and the well-being of indigenous Maya women living in a rural village in the Toledo District of southern Belize. Using a qualitative multiple methods approach, data were collected through participant observation, interviews, a focus group, and document review. Subjects were Maya women, 18 years or older, living in a rural village in southern Belize. The women demonstrated similarities in daily physical and social routines at the river and in their homes, reflecting occupational patterns and routines that are deeply imbedded in their culture and play a critical role in the formation of self-identity. Several themes emerged describing the women's definitions of health and well-being. Each woman interpreted her life in relation to her occupations and well-being differently. This seemed to vary depending on individual life experiences, routines, and contexts.