The effect of perioperative beta-blockers on patients undergoing noncardiac surgery — is the answer in?

ConclusionsThe current RCT evidence evaluating the effects of perioperative beta-blocker therapy on short and long-term cardiovascular outcomes has significant limitations. The results of these RCTs should be viewed as promising but tempered with healthy skepticism. In keeping with this the perioperative beta-blocker recommendations are weak as the reliability of the underlying evidence is weak. The POISE trial will provide definitive evidence to determine the efficacy of perioperative beta-blocker therapy.