Journal article
Update on models of pulmonary fibrosis therapy for preclinical drug research
Abstract
BACKGROUND: Idiopathic pulmonary fibrosis (IPF) is a disease with high morbidity and mortality for which current medications are not effective. Therefore, identification of potential therapies is of paramount importance. The preclinical evaluation of novel compounds in animal models represents a critical step in drug development.
OBJECTIVE: To describe features and limitations of common animal models of pulmonary fibrosis and discuss relevant …
Authors
Antoniu SA; Kolb MR
Journal
Expert Opinion on Drug Discovery, Vol. 4, No. 9, pp. 939–946
Publisher
Taylor & Francis
Publication Date
September 2009
DOI
10.1517/17460440903186100
ISSN
1746-0441