It is not known whether children with Developmental Coordination Disorder (DCD) have lower cardiorespiratory fitness (CRF) than children without the disorder, or whether this relationship varies by age and gender. These issues are examined using a cross-sectional assessment of children 9-14 years of age (N = 549). Participants were screened for DCD using the short form Bruininks-Oseretsky Test of Motor Proficiency (BOTMP-SF). A BOTMP-SF age-adjusted standard score at or below the 10th percentile rank on the BOTMP-SF was required to classify a diagnosis for probable DCD. CRF was determined from each participant’s predicted peak-aerobic power using the Léger 20-m shuttle-run test. Children with DCD report lower CRF than children without the disorder and are more likely to be in a high-risk group (≤ 20th percentile in peak VO2). Moreover, 70% of boys with DCD scored at or below the 20th percentile in peak VO2. Further research in a laboratory setting should be conducted to confirm these findings.