Journal article
EXPRESSION, LOCALIZATION, AND FUNCTION OF THE CARNITINE TRANSPORTER OCTN2 (SLC22A5) IN HUMAN PLACENTA
Abstract
L-carnitine is assumed to play an important role in fetal development, and there is evidence that carnitine is transported across the placenta. The protein involved in this transfer, however, has not been identified on a molecular level. We therefore characterized localization and function of the carnitine transporter OCTN2 in human placenta. Significant expression of OCTN2 mRNA was detected in human placenta applying real-time polymerase chain …
Authors
Grube M; Schwabedissen HMZ; Draber K; Präger D; Möritz K-U; Linnemann K; Fusch C; Jedlitschky G; Kroemer HK
Journal
Drug Metabolism and Disposition, Vol. 33, No. 1, pp. 31–37
Publisher
Elsevier
Publication Date
January 2005
DOI
10.1124/dmd.104.001560
ISSN
0090-9556