Journal article
Choice of clinical outcomes in randomized trials of heart failure therapies: Disease-specific or overall outcomes?
Abstract
BACKGROUND: There are different views regarding the appropriateness of using cause-specific events or all events as the primary outcome of clinical trials.
METHODS: This is a methodologic essay in which we discuss the pros and cons of the 2 approaches and provide illustrative examples.
Authors
Yusuf S; Negassa A
Journal
American Heart Journal, Vol. 143, No. 1, pp. 22–28
Publisher
Elsevier
Publication Date
January 2002
DOI
10.1067/mhj.2002.119770
ISSN
0002-8703