Journal article
Should angiotensin-converting enzyme-inhibitors be used to improve outcome in patients with coronary artery disease and ‘preserved’ left ventricular function?†
Abstract
Early clinical studies investigating the role of angiotensin-converting enzyme (ACE) inhibitors in the treatment of heart failure unexpectedly demonstrated a possible reduction in coronary heart disease endpoints. Two large scale clinical trials, HOPE and EUROPA, both studies in patients with coronary artery disease (CAD) but without clinical evidence of heart failure, showed a highly significant improvement in coronary heart disease outcomes …
Authors
Fox K; Ferrari R; Yusuf S; Borer JS
Journal
European Heart Journal, Vol. 27, No. 18, pp. 2154–2157
Publisher
Oxford University Press (OUP)
Publication Date
September 2006
DOI
10.1093/eurheartj/ehl122
ISSN
0195-668X