Journal article
Efficacy and safety of angiotensin receptor blockade are not modified by aspirin in patients with chronic heart failure: a cohort study from the Candesartan in Heart failure – Assessment of Reduction in Mortality and morbidity (CHARM) programme
Abstract
AIMS: It is unknown whether there is an interaction between aspirin and angiotensin receptor blockers on outcomes in patients with heart failure (HF).
METHODS AND RESULTS: The efficacy and safety of candesartan vs. placebo was assessed in 7599 patients with symptomatic HF and reduced or preserved left ventricular ejection fraction enrolled in the CHARM programme according to baseline aspirin use. Patients were randomized to candesartan or …
Authors
Chang SM; Granger CB; Johansson PA; Kosolcharoen P; McMurray JJV; Michelson EL; Murray DR; Olofsson B; Pfeffer MA; Solomon SD
Journal
European Journal of Heart Failure, Vol. 12, No. 7, pp. 738–745
Publisher
Wiley
Publication Date
7 2010
DOI
10.1093/eurjhf/hfq065
ISSN
1388-9842