Journal article
Molecular analysis of a deletion polymorphism in alpha satellite of human chromosome 17: evidence for homologous unequal crossing-over and subsequent fixation
Abstract
The human alpha satellite DNA family is organized into chromosome-specific subsets characterized by distinct higher-order repeats based on a approximately 171 basepair monomer unit. On human chromosome 17, the predominant form of alpha satellite is a 16-monomer (16-mer) higher-order repeat present in 500-1000 copies per chromosome 17. In addition, less abundant 15-monomer and 14-monomer repeats are also found constitutively on chromosome 17. …
Authors
Waye JS; Willard HF
Journal
Nucleic Acids Research, Vol. 14, No. 17, pp. 6915–6927
Publisher
Oxford University Press (OUP)
Publication Date
1986
DOI
10.1093/nar/14.17.6915
ISSN
0305-1048