Journal article
Immunocytological test to detect adult carriers of (--SEA/) deletional α-thalassaemia
Abstract
The gene frequency for (--SEA/) deletional alpha-thalassaemia is high in Southeast Asian populations. We report a simple immunocytological test that is highly sensitive and specific for the detection of adult carriers of the (--SEA/) deletion. We prospectively studied 206 consecutive adult blood samples. All 41 with the (--SEA/) deletion had a positive test; all but 1 of the 165 non-carriers were negative. This test, whose major requirement is …
Authors
Tang W; Luo H-Y; Eng B; Waye JS; Chui DHK
Journal
The Lancet, Vol. 342, No. 8880, pp. 1145–1147
Publisher
Elsevier
Publication Date
11 1993
DOI
10.1016/0140-6736(93)92125-d
ISSN
0140-6736