Hb North York [β117(G19)His→Asp]: A New β Chain Hemoglobin Variant Journal Articles

abstract

• Routine hemoglobin (Hb) analysis identified a new beta chain Hb variant in an Iranian woman, who otherwise had normal hematological indices. Sequence analysis demonstrated that the Hb variant was due to a missense mutation at amino acid codon 117 (CAC>GAC, His-->Asp) of the beta-globin gene.

authors

• Waye, John
• Walker, Lynda
• Nakamura, Lisa M
• Eng, Barry
• McFarlane, Andrew

status

• published 

publication date

• January 2009

has subject area

• 1103 Clinical Sciences (FoR)
• Adult (MeSH)
• Aspartic Acid (MeSH)
• DNA Mutational Analysis (MeSH)
• Female (MeSH)
• Hemoglobins, Abnormal (MeSH)
• Histidine (MeSH)
• Humans (MeSH)
• Immunology (Science Metrix)
• Iran (MeSH)
• Mutation, Missense (MeSH)
• beta-Globins (MeSH)

published in

• Hemoglobin  Journal

keywords

• Adult
• Aspartic Acid
• DNA Mutational Analysis
• Female
• Hemoglobins, Abnormal
• Histidine
• Humans
• Iran
• Mutation, Missense
• beta-Globins

Digital Object Identifier (DOI)

• 10.1080/03630260802625659

PubMed ID

• 19205973

start page

• 51

end page

• 53

volume

• 33

issue

• 1