Journal article
Phase I study of decitabine in combination with vorinostat in patients with advanced solid tumors and non-Hodgkin's lymphomas.
Abstract
PURPOSE: This phase I study evaluated the safety, tolerability, pharmacokinetics and preliminary efficacy of the combination of decitabine with vorinostat. PATIENTS AND METHODS: Patients with advanced solid tumors or non-Hodgkin's lymphomas were eligible. Sequential and concurrent schedules were studied. RESULTS: Forty-three patients were studied in 9 different dose levels (6 sequential and 3 concurrent). The maximum tolerated dose (MTD) on …
Authors
Stathis A; Hotte SJ; Chen EX; Hirte HW; Oza AM; Moretto P; Webster S; Laughlin A; Stayner L-A; McGill S
Journal
Clinical Cancer Research, Vol. 27, No. 15S, pp. 3528–3528
Publisher
American Society of Clinical Oncology (ASCO)
Publication Date
May 20, 2009
DOI
10.1200/jco.2009.27.15_suppl.3528
ISSN
1078-0432