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Impact of temperature on cell death in a...
Journal article

Impact of temperature on cell death in a cell-culture model of hepatocellular carcinoma.

Abstract

BACKGROUND: Radiofrequency ablation (RFA) is one treatment option for hepatocellular carcinoma (HCC) where tumour cells are destroyed by heat. However, there is lack of knowledge about cellular reactions after heating. Therefore, we studied cell death after heat application in a cell-culture setting mimicking HCC. MATERIALS AND METHODS: Intracellularly stained hepatic stellate cells (LX-1) and HCC cells (HepG2) were cultivated in co-culture or …

Authors

Leber B; Mayrhauser U; Leopold B; Koestenbauer S; Tscheliessnigg K; Stadlbauer V; Stiegler P

Journal

Anticancer Research, Vol. 32, No. 3, pp. 915–921

Publication Date

March 2012

ISSN

0250-7005