Laboratory Investigation of Myeloproliferative Neoplasms (MPNs) Academic Article uri icon

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abstract

  • OBJECTIVES: To standardize diagnostic investigations for myeloproliferative neoplasms (MPNs) to increase homogeneity in patient care and to streamline diagnostic approaches in the most efficient and cost-effective manner. METHODS: The development of Canadian expert consensus recommendations for the diagnosis of MPNs began with a review of the following: clinical evidence, daily practice, existing treatment guidelines, and availability of diagnostic tools. Each group member was assigned a specific topic, which they discussed with the entire group during several consensus meetings. RESULTS: This document provides the Canadian MPN group's recommendations, proposed diagnostic algorithms, and background evidence upon which decisions were made. CONCLUSIONS: Standardization of diagnostic investigations will increase homogeneity in patient care and provide a foundation for future clinical research in this rapidly evolving therapeutic area. Streamlining diagnostic approaches in the most efficient and cost-effective manner will also result in significant cost saving for the health care system.

authors

  • Busque, Lambert
  • Porwit, Anna
  • Day, Radmila
  • Olney, Harold J
  • Leber, Brian
  • Éthier, Vincent
  • Sirhan, Shireen
  • Foltz, Linda
  • Prchal, Jaroslav
  • Kamel-Reid, Suzanne
  • Karsan, Aly
  • Gupta, Vikas

publication date

  • October 2016