Journal article
[3H] Melatonin Binding in Membrane and Cytosol Fractions From Rat and Calf Brain
Abstract
The binding characteristics of the tritiated pineal hormone, [3H] melatonin, were studied in brain tissues using in vitro binding techniques. In synaptosomal membranes prepared from rat hippocampus and subjected to preincubation at 37 degrees C and multiple washings, high-affinity binding of [3H] melatonin significantly exceeds that previously reported for membrane or cytosol fractions from mammalian brain. Scatchard analysis of saturation …
Authors
Niles LP
Journal
Journal of Pineal Research, Vol. 4, No. 1, pp. 89–98
Publisher
Wiley
Publication Date
January 1987
DOI
10.1111/j.1600-079x.1987.tb00844.x
ISSN
0742-3098