Journal article
Endogenous cholecystokinin and intestinal satiety
Abstract
The role of endogenous cholecystokinin (CCK) as a mediator of intestinal satiety is examined. We used rats equipped with a chronic gastric fistula and an indwelling duodenal catheter to assess the effects of direct duodenal stimulation on sham feeding. To evaluate the contribution of endogenous CCK to intestinal satiety we used a specific competitive antagonist of the satiety action of CCK, proglumide. Intraduodenal infusion of 11 or 5 ml …
Authors
Collins SM; Conover KL; Forsyth PA; Weingarten HP
Journal
American Journal of Physiology, Vol. 249, No. 6, pp. r667–r671
Publisher
American Physiological Society
Publication Date
December 1, 1985
DOI
10.1152/ajpregu.1985.249.6.r667
ISSN
0002-9513