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Inflammation causes hyperplasia and hypertrophy in...

Journal article

Inflammation causes hyperplasia and hypertrophy in smooth muscle of rat small intestine

Abstract

Inflammation of the rat jejunum with Trichinella spiralis causes altered smooth muscle contractility by day 6 postinfection (PI). We investigated the association of structural change in the smooth muscle layers with inflammation. By day 6 PI, smooth muscle area in cross sections of jejunum increased (P less than 0.05) in longitudinal (LM) and circular (CM) muscle layers. Nuclei counting in cross sections showed that cell number increased two- …

Authors

Blennerhassett MG; Vignjevic P; Vermillion DL; Collins SM

Journal

American Journal of Physiology-Gastrointestinal and Liver Physiology, Vol. 262, No. 6, pp. G1041–G1046

Publisher

American Physiological Society

Publication Date

June 1, 1992

DOI

10.1152/ajpgi.1992.262.6.g1041

ISSN

0193-1857

Associated Experts

Peter Vignjevic

Assistant Clinical Professor, Faculty of Health Sciences

Labels

Medical Subject Headings (MeSH)

Animals DNA Replication Hypertrophy Ileum Inflammation Intestine, Small Jejunum Larva Male Mice Mice, Inbred CBA Muscle, Smooth Rats Rats, Inbred Strains Reference Values Thymidine Trichinella Trichinellosis Tritium

Fields of Research (FoR)

3202 Clinical sciences 3208 Medical physiology

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