Multi-component assessment of worker exposures in a copper refinery Part 2. Biological exposure indices for copper, nickel and cobalt

Urinary copper (Cu), nickel (Ni) and cobalt (Co) concentrations were determined for 127 Cu refinery workers (40 females, 87 males), with values of the 95% upper confidence interval of the geometric mean in nmol per mmol creatinine of 89 (Ni), 42 (Cu) and 3.4 (Co) for electrorefinery workers. In the pyrometallurgical departments, the corresponding concentrations were 37 (Ni), 99 (Cu) and 11 (Co). Female workers had higher Co urinary …