Journal article
Peroxynitrite and nitric oxide differ in their effects on pig coronary artery smooth muscle
Abstract
Peroxynitrite generated in arteries from superoxide and nitric oxide (NO) may damage their function. Here, we compare the effects of peroxynitrite and peroxynitrite/NO-generating agents SIN-1 (3-morpholinosydnonimine hydrochloride), SNAP (S-nitroso-N-acetyl-penicillamine), SNP (sodium nitroprusside), and NONOate (spermine NONOate) on pig coronary artery. Deendothelialized artery rings were pretreated with these agents and then washed before …
Authors
Walia M; Samson SE; Schmidt T; Best K; Whittington M; Kwan CY; Grover AK
Journal
American Journal of Physiology - Cell Physiology, Vol. 284, No. 3, pp. c649–c657
Publisher
American Physiological Society
Publication Date
March 1, 2003
DOI
10.1152/ajpcell.00405.2002
ISSN
0363-6143
Associated Experts
Fields of Research (FoR)
Medical Subject Headings (MeSH)
AnimalsCalcium SignalingCalcium-Transporting ATPasesCell MembraneCoronary Artery DiseaseCoronary VesselsEnzyme InhibitorsFree Radical ScavengersMuscle ContractionMuscle, Smooth, VascularMyocytes, Smooth MuscleNitric OxideNitric Oxide DonorsOxidative StressPeroxynitrous AcidSarcoplasmic Reticulum Calcium-Transporting ATPasesSwineTransport Vesicles