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Store operated Ca2+ entry dependent contraction of...
Journal article

Store operated Ca2+ entry dependent contraction of coronary artery smooth muscle: Inhibition by peroxide pretreatment

Abstract

The sarco/endoplasmic reticulum (SER) Ca(2+) pool is refilled by the SER Ca(2+) pump (SERCA) using cytosolic Ca(2+) and/or extracellular Ca(2+) entering the cell. The effects of the SERCA pump inhibitor cyclopiazonic acid (CPA) were studied in pig coronary artery smooth muscle using two protocols. In protocol A, the SERCA pump was inhibited by adding CPA to cells/tissues in Ca(2+)-containing solution, whereas in protocol B, CPA was added to …

Authors

Pande J; Dimmers G; Akolkar G; Skelley L; Samson SE; Grover AK

Journal

Cell Calcium, Vol. 51, No. 2, pp. 149–154

Publisher

Elsevier

Publication Date

February 2012

DOI

10.1016/j.ceca.2011.12.001

ISSN

0143-4160