Journal article
Induction of mitochondrial fusion by cysteine‐alkylators ethacrynic acid and N‐ethylmaleimide
Abstract
Mitochondrial fusion and fission are important aspects of eukaryotic cell function that permit the adoption of varied mitochondrial morphologies depending upon cellular physiology. We previously observed that ethacrynic acid (EA) induced mitochondrial fusion in cultured BSC-1 and CHO/wt cells. However, the mechanism responsible for it was not clear since EA has a number of known cellular effects including glutathione (GSH) depletion and …
Authors
Bowes TJ; Gupta RS
Journal
Journal of Cellular Physiology, Vol. 202, No. 3, pp. 796–804
Publisher
Wiley
Publication Date
March 2005
DOI
10.1002/jcp.20178
ISSN
0021-9541