Effects of Melatonin and Epiphyseal Proteins on Fluoride‐Induced Adverse Changes in Antioxidant Status of Heart, Liver, and Kidney of Rats

Abstract

Several experimental and clinical reports indicated the oxidative stress-mediated adverse changes in vital organs of human and animal in fluoride (F) toxicity. Therefore, the present study was undertaken to evaluate the therapeutic effect of buffalo (Bubalus bubalis) epiphyseal (pineal) proteins (BEP) and melatonin (MEL) against F-induced oxidative stress in heart, liver, and kidney of experimental adult female rats. To accomplish this …