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Detection of circulating ‘terminal...
Journal article

Detection of circulating ‘terminal transferase-positive’ cells does not predict relapse in acute lymphoblastic leukemia

Abstract

Serial samples of peripheral blood were obtained from 35 children with ALL over a period of 18 months. The mononuclear cells were examined for TdT by indirect immunofluorescence using an unpurified anti-calf thymus TdT as the primary antibody. This analysis failed to distinguish those children who were destined to relapse (n = 9) from those who remained in continuous complete remission. Rather, the exhibition of fluorescence was linked to the …

Authors

Barr RD; Koekebakker M

Journal

Leukemia Research, Vol. 8, No. 6, pp. 1051–1055

Publisher

Elsevier

Publication Date

January 1984

DOI

10.1016/0145-2126(84)90060-2

ISSN

0145-2126