Journal article
The intracellular location of terminal transferase does not vary with cell cycle stage
Abstract
The biochemical activity of terminal transferase (TdT) in the thymocytes of leukemic AKR mice has no relationship to cell cycle stage, unlike the activity of replicative DNA polymerase which increases during the period of DNA synthesis. Moreover, such assays of DNA polymerase alpha reveal a shift in enzyme activity from cytoplasm to nucleus during S phase. In the present study, the role of TdT in DNA metabolism was explored further by examining …
Authors
Barr RD; Barresi T; Koekebakker M; Sarin PS
Journal
Leukemia Research, Vol. 8, No. 3, pp. 425–428
Publisher
Elsevier
Publication Date
January 1984
DOI
10.1016/0145-2126(84)90082-1
ISSN
0145-2126