Journal article
The agonist (d-leu-6,des-gly-10)-LHRH-ethylamide does not protect the fecundity of rats exposed to high dose unilateral ovarian irradiation
Abstract
Attempts to protect the ovary from the toxic effects of radiation and chemotherapy are relevant to the management of the young patient with cancer. Previous studies in a variety of animal species with several types of agonists of GnRH have shown promise in affording gonadal protection using indirect indices of reproductive function. The current investigations are based on these observations. Female rats were treated with (d-leu-6,des-gly-10) …
Authors
Jarrell JF; McMahon A; Barr RD; YoungLai EV
Journal
Reproductive Toxicology, Vol. 5, No. 4, pp. 385–388
Publisher
Elsevier
Publication Date
1991
DOI
10.1016/0890-6238(91)90098-z
ISSN
0890-6238