Journal article
Abnormal Biochemistry of Vascular Smooth Muscle Plasma Membrane as an Important Factor in the Initiation and Maintenance of Hypertension in Rats
Abstract
Tissue wet weight as well as total protein content, 5'-nucleotidase activity, alkaline phosphatase activity and Ca2+ accumulation associated with a plasma membrane fraction isolated from spontaneous hypertensive rats (SHR) and rats with deoxycorticosterone (DOC) induced hypertension were investigated. Enhanced alkaline phosphatase activity and reduced ATP-dependent Ca2+ accumulation preceded the development of hypertension in SHR and these …
Authors
Kwan C-Y; Belbeck L; Daniel EE
Journal
Blood Vessels, Vol. 16, No. 5, pp. 259–268
Publisher
Karger Publishers
Publication Date
1979
DOI
10.1159/000158214
ISSN
0303-6847