Chloride removal selectively inhibits phasic contractions of guinea pig ileal longitudinal smooth muscle Academic Article uri icon

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abstract

  • Removal of external chloride selectively and reversibly inhibits the phasic responses of the guinea pig ileal longitudinal muscle to high potassium and cholinergic stimulation. The binding of calcium to a relatively superficial pool is affected by chloride removal. Alterations in anionic composition of bathing solution affects the availability of calcium for excitation--contraction (E--C) coupling in smooth muscle.

publication date

  • December 1982