Effect of tris buffer on the contractile responses of rat vas deferens

The influences of Tris-(hydroxymethyl)aminomethane (Tris) on the contractile responses of rat vas deferens to norepinephrine (NE), potassium chloride (KCl) and field stimulation were investigated. Equilibration of rat vas deferens muscle strips in Tris containing Tyrode medium caused a significant increase in sensitivity to KCl, but had no effect on the maximum tension induced by NE or KCl. The biphasic responses to 10(-4) M NE and 100 mM KCl, …